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Caprion’s E.Coli Treatment Shows Promise

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Caprion Pharmaceuticals completed Phase I studies for Shigamabs, its product for the treatment of Shigatoxin-producing E. coli infections (STEC), including the O157:H7 strain involved in the current U.S. outbreak. The severe clinical symptoms such as hemorrhagic colitis, thrombocytopenia, hemolytic anemia and hemolytic uremic syndrome in as many as 60% of all infected patients, are potentially lethal in the most severe cases. Serious complications are most frequent in young children and the elde...

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